Mission: Establishing foundational design principles for engineering biological systems. We deploy AI-accelerated strain design and programming to enable rapid customization of high-performance industrial microbial chassis. Engineered strains for strategic biobased chemicals, platform molecules, and pharmaceutical intermediates will be scaled to industrial production. Advanced microbial cultivars, synthetic consortia, and elite crop varieties will enhance productivity on saline-alkali lands. This mission-driven research aims to achieve transformative innovation in core strain development, ensure food security, and advance China's global leadership in biomanufacturing.