Education
Degree |
Date |
Affiliation |
Major |
PhD |
2013.6 |
Shandong University |
Microbiology |
Bachelor |
2008.6 |
Shandong University |
Biological science |
Research Experience
Date |
Affiliation |
Position |
2018.9-now |
Microbial technology institute, Shandong University |
Associate Professor |
2018.1-2018.8 |
Microbial technology institute, Shandong University |
Lecturer |
2013.9-2017.12 |
School of life science, Shandong University |
Lecturer |
Research Interests
1. Bacteriophage of lactic acid bacteria and the potential application
2. Physiological genetics research of lactic acid bacteria
3 Gut lactic acid bacteria
Research Projects
1. 2017.7-2020.12Exploitation of intestinal probiotics resource based on Chinese people and dietary features.National Key Research and Development Program of China. Participant
2. 2015.01-2017.12 Genome editing technology in lactic acid bacteria using CRISPR/Cas system.National Science Foundation for Young Scientists of China. Host
3. 2015.07-2017.12 Construction and potential application of highly active and broad-spectrum antimicrobial developed from phage endolysin.China Postdoctoral Science FoundationSpecial Project. Host
4. 2014.07-2016.12 Oligomeric state and lysis control mechanism of holin protein ofLactobacillus bacteriophage.China Postdoctoral Science Foundation Funded GeneralProject. Host
Representative Publications
1. Yongping Xin#, Yingli Mu, Jian Kong, Tingting Guo*. 2019. Targeted and repetitive chromosomal integration enables high yield of heterologous gene expression inLactobacillus casei,Appl Environ Microbiol 85:e00033-19.
2.Tingting Guo#, Yongping Xin#, Yi Zhang, Xinyi Gu, Jian Kong*. 2019. A rapid and versatile tool for genomic engineering inLactococcus lactis.Microb Cell Fact 18:22.
3.Tingting Guo#, Yongping Xin, Chenchen Zhang, Jian Kong*. 2018. A cytoplasmic antiholin is embedded in-frame with the holin in aLactobacillus fermentum bacteriophage.Appl Environ Microbiol 84:e02518-17.
4.Tingting Guo#, Li Zhang, Yongping Xin, Zhenshang Xu, Huiying He, Jian Kong*. 2017 Oxygen-Inducible Conversion of Lactate to Acetate in HeterofermentativeLactobacillus brevis ATCC 367. Appl Environ Microbiol 83:e01659-17.
5.Tingting Guo#, Xudong Ouyang, Yongping Xin, Yue Wang, Susu Zhang, Jian Kong*. 2016. Characterization of a New Cell Envelope Proteinase PrtP from Lactobacillus rhamnosus CGMCC11055.J Agric Food Chem, 2016, 64(37): 6985-6992.
6. Tingting Guo#, Chenchen Zhang, Yongping Xin, Min Xin, Jian Kong*. 2016. A novel chimeric prophage vB_LdeS phiJB from commercial Lactobacillus delbrueckii subsp. bulgaricus.J Ind Microbiol Biotechnol 43(5):681-689.
7.Tingting Guo#, Yongping Xin, Chechen Zhang, Xudong Ouyang, Jian Kong*. 2016. The potential of the endolysin Lysdb fromLactobacillus delbrueckii phage for combatingStaphylococcus aureus during cheese manufacture from raw milk.Appl Microbiol Biotechnol 100(8):3545-54.
8. Tingting Guo#, Chenchen Zhang, Wei Liu, Shaohua Wang, Jian Kong*. 2015. Functional analysis of the N-terminal region of endolysin Lyb5 encoded byLactobacillus fermentum bacteriophage φPYB5.Int J Food Microbiol 203:1-7.
Patents
1 Jian Kong, Tingting Guo, Chenchen Zhang, Liying Han, Ting Wang;The invention relates to a preparation method, product and application of a liquid yogurt starter;patent number: ZL201410475760.8
2 Jian Kong, Tingting Guo, Ting Wang, Xiaotong Gao;AStreptococcus thermophilus withγ-aminobutyric acid and glutathione synthesis ability and its application;patent number: ZL201410480097.0
3 Jian Kong, Tingting Guo, Xudong Ouyang, Yongping Xin;ALactobacillus rhamnosus with cell membrane protease and its application; patent number: ZL20151064605.5.
