faculty

Xiuyun Wu

Release date:2025-07-31    Author:     Editor: 张凌娇    Click:

Xiuyun Wu

Research Assistant

Master Supervisor

Tel:15054198651

E-mail:wuxiuyun@sdu.edu.cn

     


Education

09/2013-06/2018   PhD, Microbiology, School of Life Sciences, Shandong University

09/2009-07/2013  Bachelor, Biotechnology, School of Life Sciences, Qingdao Agricultural University


Research Experience

06/2018-02/2022  Post doctor, State Key Laboratory of Microbial Technology


Research Interests

1.Green transformation of biomass polysaccharides.

2.Catalytic mechanism of thermophilic enzymes.

3.Rational design of carbohydrate-active enzymes.


Research Projects

01/2022-12/2024  National Natural Science Foundation of China Insight into molecular mechanism of processive catalysis of thermophilic chitinase SsChi18A (No. 32100022)


Representative Publications

1.Xiuyun Wu, Zelu Shi, Wenya Tian, Mengyu Liu, Shuxia Huang, Xinli Liu, Hua Yin* and Lushan Wang*, A thermostable and CBM2-linked GH10 xylanase from Thermobifida fusca for paper bleaching. Front. Bioeng. Biotechnol. 2022, 10:939550. doi: 10.3389/fbioe.2022.939550

2.Xiuyun Wu, Shu Zhang, Sha Zhao, Lin Dai, Shuxia Huang, Xinli Liu, Junhong Yu* and Lushan Wang*. Functional Specificity of Three α‑Arabinofuranosidases  from Different Glycoside Hydrolase Families in Aspergillus niger An76. J. Agric. Food Chem. 2022, 70, 5039−5048 https://doi.org/10.1021/acs.jafc.1c08388

3.Guomeng Sha, Lili Zhang, Xiuyun Wu, Tong Chen, Xiaohong Tao, Xin Li, Jianguo Shen, Guanjun Chen, Lushan Wang*. Integrated meta-omics study on rapid   tylosin removal mechanism and dynamics of antibiotic resistance genes during aerobic thermophilic fermentation of tylosin mycelial dregs. Bioresource Technology 2022, 351:127010. https://doi.org/10.1016/j.biortech.2022.127010

4.Shu Zhang, Sha Zhao, Weihao Shang, Zijuan Yan, Xiuyun Wu *, Yingjie Li, Guanjun Chen, Xinli Liu, Lushan Wang. Synergistic mechanism of GH11 xylanases with different action modes from Aspergillus niger An76. Biotechnol Biofuels. 2021 May 10;14(1):118. doi: 10.1186/s13068-021-01967-1.

5.Yuxuan Song, Xiuyun Wu, Yue Zhao, Xukai Jiang*, Lushan Wang. Comparative molecular dynamics simulations identify a salt-sensitive loop responsible for the halotolerant activity of GH5 cellulases. J Biomol Struct Dyn. 2021 May 27:1-11. doi: 10.1080/07391102.2021.1930167.

6.Xiuyun Wu, Shu Zhang, Qun Zhang, Yue Zhao, Guanjun Chen, Weihua Guo and Lushan Wang*. The contribution of specific subsites to catalytic activities in      active site architecture of GH11 xylanase. Appl Microbiol Biotechnol 2020, 104: 8735-8745 doi: 10.1007/s00253-020-10865-9.

7.Xiuyun Wu, Qun Zhang, Lanzeng Zhang, Shijia Liu, Guanjun Chen, Huaiqiang Zhang and Lushan Wang*. Insights into the role of exposed surface charged          residues in the alkali-tolerance of GH11 xylanase. Front Microbiol. 2020, 11:872. doi: 10.3389/fmicb.2020.00872

8.Xiuyun Wu, Zhennan Tian, Xukai Jiang, Qun Zhang, Lushan Wang*. Enhancement in catalytic activity of Aspergillus niger XynB by selective site-directed        mutagenesis of active site amino acids. Appl Microbiol Biotechnol, 2018, 102:249–260.


Adress:State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao 266237, P.R. China

Tel: (86)-0532-58631501  (86)-0532-58631597  Post Code: 266237

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