Xiuyun Wu Research Assistant Master Supervisor Tel:15054198651 E-mail:wuxiuyun@sdu.edu.cn |
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09/2013-06/2018 PhD, Microbiology, School of Life Sciences, Shandong University
09/2009-07/2013 Bachelor, Biotechnology, School of Life Sciences, Qingdao Agricultural University
06/2018-02/2022 Post doctor, State Key Laboratory of Microbial Technology
1.Green transformation of biomass polysaccharides.
2.Catalytic mechanism of thermophilic enzymes.
3.Rational design of carbohydrate-active enzymes.
01/2022-12/2024 National Natural Science Foundation of China Insight into molecular mechanism of processive catalysis of thermophilic chitinase SsChi18A (No. 32100022)
Representative Publications |
1.Xiuyun Wu, Zelu Shi, Wenya Tian, Mengyu Liu, Shuxia Huang, Xinli Liu, Hua Yin* and Lushan Wang*, A thermostable and CBM2-linked GH10 xylanase from Thermobifida fusca for paper bleaching. Front. Bioeng. Biotechnol. 2022, 10:939550. doi: 10.3389/fbioe.2022.939550
2.Xiuyun Wu, Shu Zhang, Sha Zhao, Lin Dai, Shuxia Huang, Xinli Liu, Junhong Yu* and Lushan Wang*. Functional Specificity of Three α‑Arabinofuranosidases from Different Glycoside Hydrolase Families in Aspergillus niger An76. J. Agric. Food Chem. 2022, 70, 5039−5048 https://doi.org/10.1021/acs.jafc.1c08388
3.Guomeng Sha, Lili Zhang, Xiuyun Wu, Tong Chen, Xiaohong Tao, Xin Li, Jianguo Shen, Guanjun Chen, Lushan Wang*. Integrated meta-omics study on rapid tylosin removal mechanism and dynamics of antibiotic resistance genes during aerobic thermophilic fermentation of tylosin mycelial dregs. Bioresource Technology 2022, 351:127010. https://doi.org/10.1016/j.biortech.2022.127010
4.Shu Zhang, Sha Zhao, Weihao Shang, Zijuan Yan, Xiuyun Wu *, Yingjie Li, Guanjun Chen, Xinli Liu, Lushan Wang. Synergistic mechanism of GH11 xylanases with different action modes from Aspergillus niger An76. Biotechnol Biofuels. 2021 May 10;14(1):118. doi: 10.1186/s13068-021-01967-1.
5.Yuxuan Song, Xiuyun Wu, Yue Zhao, Xukai Jiang*, Lushan Wang. Comparative molecular dynamics simulations identify a salt-sensitive loop responsible for the halotolerant activity of GH5 cellulases. J Biomol Struct Dyn. 2021 May 27:1-11. doi: 10.1080/07391102.2021.1930167.
6.Xiuyun Wu, Shu Zhang, Qun Zhang, Yue Zhao, Guanjun Chen, Weihua Guo and Lushan Wang*. The contribution of specific subsites to catalytic activities in active site architecture of GH11 xylanase. Appl Microbiol Biotechnol 2020, 104: 8735-8745 doi: 10.1007/s00253-020-10865-9.
7.Xiuyun Wu, Qun Zhang, Lanzeng Zhang, Shijia Liu, Guanjun Chen, Huaiqiang Zhang and Lushan Wang*. Insights into the role of exposed surface charged residues in the alkali-tolerance of GH11 xylanase. Front Microbiol. 2020, 11:872. doi: 10.3389/fmicb.2020.00872
8.Xiuyun Wu, Zhennan Tian, Xukai Jiang, Qun Zhang, Lushan Wang*. Enhancement in catalytic activity of Aspergillus niger XynB by selective site-directed mutagenesis of active site amino acids. Appl Microbiol Biotechnol, 2018, 102:249–260.