Longyang Dian

Release date:2020-08-31    Author:     Editor: Liyuan    Click:










Tianjin University

Applied Chemistry



Tianjin University

Medicinal Chemistry



Sun Yat-Sen University


Research Experience





Technion-Israel Institute Technology

Senior Researcher


The University of Manchester

Research Associate

Research Interests

1 the development of organic synthetic methodology to creat noval C-C bond, C-X bond and stereo centers in an efficient and economic pathway, especially the atom-economic and environmental friendly transformations.

2 the application of novel synthetic methodology in the late-staged functionalization of biologically active natural products, bioorthogonal reactions and the optimization of drug synthetic technology

3 the design, assemble and application of bioinspired artificial materials.

Research Projects

Qilu Young Scholar First Level Talent Start Funding (2020-2025)

Representative Publications

16.Dian L., Marek I.*Cobalt-Catalyzed Diastereoselective and Enantioselective Hydrosilylation of Achiral Cyclopropenes.Org. Lett.2020,22, 4914; (IF:6.091)

15.Dian L., Marek I.*Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes.ACS Catal.2020,10, 1289-1293; (IF:12.350)

14.Dian L., Marek I.*Asymmetric Preparation of Polysubstituted Cyclopropanes Based on Direct Functionalization of Achiral Three-Membered Carbocycles.Chem. Rev.,2018, 118, 8415; (Invited review,IF:52.758)

13.Dian L., Marek I.*Rh-Catalyzed Arylation of Cyclopropenes Based on Asymmetric Direct Functionalization of Three-Membered Carbocycles.Angew. Chem. Int. Ed.,2018,57, 3682;Angew. Chem.,2018,130, 3744; (IF:12.959)

Highlighted by SYNFACTS2018,14, 0521

Collection of 54th Bürgenstock Conference

12.Dian L., Xing Q., Zhang-Negrerie D., Du Y.*Direct Functionalization of Alkyl Ethers to Construct Hemiaminal Ether Skeletons (HESs).Org. Biomol. Chem.,2018,16, 4384; (IF:3.490)

11.Dian L., Müller D. S., Marek I.*Asymmetric Copper-Catalyzed Carbomagnesiation of Cyclopropenes.Angew. Chem. Int. Ed.,2017,56, 6783;Angew. Chem.,2017,129, 6887; (IF:12.959)

Highlighted by SYNFACTS2017,13, 0951

10.Dian L., Zhang-Negrerie D., Du Y.*Transition-Metal-Free Oxidative Cross-Coupling C(sp2)-C(sp3) Bond Formation: Regioselective C3-Alkylation of Coumarins with Tertiary Amines.Adv. Synth. Catal.,2017,359, 3090; (IF:5.851)

9.Dian L., Zhao H., Zhang-Negrerie D., Du Y.*Cobalt-Catalyzed Twofold Direct C(sp2)−C(sp3) Bond Coupling: Regioselective C-3 Alkylation of Coumarins with (Cyclo)alkyl Ethers.Adv. Synth. Catal.,2016,358, 2422; (IF:5.851)

Abstracted byChemInform,2016,47, 51

Special issue ofBase-metal catalysisedited by Prof.M. Christina Whiteand Prof.Alois Fürstner

8.Dian L., Wang S., Zhang-Negrerie D., Du Y.* Organocatalytic Radical Involved Oxidative Cross-Coupling ofN-Hydroxyphthalimide with Benzylic and Allylic Hydrocarbons.Adv. Synth. Catal.,2015,357, 3836; (IF:5.851)

Abstracted byChemInform,2016,47, 17

7.Dong, T., Li, C., Wang, X.,Dian, L., Zhang, X., Chen, X., Li, L., Cao, R., Huang, N., He, S., Lei, X.* Ainsliadimer A Selectively Inhibits IKKα/β by Covalently Binding a Conserved Cysteine.Nat. Commun.,2015,6, 6522; (IF:12.353)

News story describing this work was highlighted inChem. & Eng. News,2015,15, 39

6.Dian L., Wang S., Zhang-Negrerie D., Du Y.*, Zhao K. Organocatalytic Amination of Alkyl Ethersvia n-Bu4NI/t-BuOOH Mediated Intermolecular Oxidative C(sp3)–N Bond Formation: Novel Synthesis of Hemiaminal Ethers.Chem. Commun.,2014,50, 11738; (IF:6.164)

Abstracted byChemInform,2015, DOI: 10.1002/chin.201509058

One of the 25 most-down loaded in Q3 of2015

5. Zheng Z.,Dian L., Yuan Y., Zhang-Negrerie D., Du Y.*, Zhao K.*PhI(OAc)2-Mediated Intramolecular Oxidative Aryl-Aldehyde Csp2-Csp2Bond Formation: Metal-free Synthesis of Acridone Derivatives.J. Org. Chem.,2014,79,7451;(IF:4.335)

Abstracted byChemInform,2015, DOI: 10.1002/chin.201507225

4.Li C., Dong T.,Dian L., Zhang W., Lei X.* Biomimetic Syntheses and Structural Elucidation of the Apoptosis-inducing Sesquiterpenoid Trimers: (−)-Ainsliatrimers A and B.Chem. Sci.,2013,4, 1163;(IF:9.346)

3. Li, C.,Dian L., Zhang W., Lei X.*Biomimetic Syntheses of (−)-Gochnatiolides A−C and (−)-Ainsliadimer B.J. Am. Chem. Soc.,2012,134, 12414; (IF:14.357)

2.Leng J.-D.,Dian L.-Y., Liu J.-L., Tong M.-L.* Two MnIII4MnII8 Clusters From the Use of Tripodal Ligands Showing Single-Molecule Magnet Behavior.Polyhedron,2011,30, 3088;(IF:2.067)

1.Leng J.-D.,Dian L.-Y., Liu J.-L., Tong M.-L.* A Series of MnIII4MnII8 Single-Molecule Magnets Mediated by Intra- and Intermolecular Interactions.Eur. J. Inorg. Chem.,2011, 2317.(IF:2.507)

Honors and awards

5. Tianjin University Distinguished Graduate (Tianjin University, 2015)

4. First Award in the “P & G” Doctoral Candidates Forum of Tianjin University 6th Sub-session of SPST (Tianjin University, 2014)

3. Excellent Ph.D. Candidate Fund Support of Tianjin University (Tianjin University, 2014)

2. Graduate Scholarship of Tianjin University (Tianjin University, 2010, 2011)

1. Outstanding Student Scholarship of Sun Yat-Sen University (Sun Yat-Sen University, 2007, 2008, 2009)

Adress:State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao 266237, P.R. China

Tel: (86)-0532-58631501  (86)-0532-58631597  Post Code: 266237

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