faculty

Introduction Of Faculty Outstanding Talents Current Faculty

Pharmaceutical Microbial Technology Resource And Environmental Microbial Technology Industrial Microbial Technology Marine Microbial Technology

Home > faculty > Current Faculty > Pharmaceutical Microbial Technology > Professor & Research Fellow > Content

Longyang Dian

Release date：2020-08-31 Author： Editor： Liyuan Click：

website：

https://www.x-mol.com/groups/longyang-dian?lang=en

Education

Degree	Date	Affiliation	Major
PhD	2012-2015	Tianjin University	Applied Chemistry
Master	2010-2012	Tianjin University	Medicinal Chemistry
Bachelor	2006-2010	Sun Yat-Sen University	Chemistry

Research Experience

Date	Affiliation	Position
2015-2018	Technion-Israel Institute Technology	Senior Researcher
2018-2019	The University of Manchester	Research Associate

Research Interests

1 the development of organic synthetic methodology to creat noval C-C bond, C-X bond and stereo centers in an efficient and economic pathway, especially the atom-economic and environmental friendly transformations.

2 the application of novel synthetic methodology in the late-staged functionalization of biologically active natural products, bioorthogonal reactions and the optimization of drug synthetic technology

3 the design, assemble and application of bioinspired artificial materials.

Research Projects

Qilu Young Scholar First Level Talent Start Funding (2020-2025)

Representative Publications

16.Dian L., Marek I.*Cobalt-Catalyzed Diastereoselective and Enantioselective Hydrosilylation of Achiral Cyclopropenes.Org. Lett.2020,22, 4914; (IF：6.091)

15.Dian L., Marek I.*Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes.ACS Catal.2020,10, 1289-1293; (IF：12.350)

14.Dian L., Marek I.*Asymmetric Preparation of Polysubstituted Cyclopropanes Based on Direct Functionalization of Achiral Three-Membered Carbocycles.Chem. Rev.,2018, 118, 8415; (Invited review，IF：52.758)

13.Dian L., Marek I.*Rh-Catalyzed Arylation of Cyclopropenes Based on Asymmetric Direct Functionalization of Three-Membered Carbocycles.Angew. Chem. Int. Ed.,2018,57, 3682;Angew. Chem.,2018,130, 3744; (IF：12.959)

Highlighted by SYNFACTS2018,14, 0521

Collection of 54th Bürgenstock Conference

12.Dian L., Xing Q., Zhang-Negrerie D., Du Y.*Direct Functionalization of Alkyl Ethers to Construct Hemiaminal Ether Skeletons (HESs).Org. Biomol. Chem.,2018,16, 4384; (IF：3.490)

11.Dian L., Müller D. S., Marek I.*Asymmetric Copper-Catalyzed Carbomagnesiation of Cyclopropenes.Angew. Chem. Int. Ed.,2017,56, 6783;Angew. Chem.,2017,129, 6887; (IF：12.959)

Highlighted by SYNFACTS2017,13, 0951

10.Dian L., Zhang-Negrerie D., Du Y.*Transition-Metal-Free Oxidative Cross-Coupling C(sp2)-C(sp3) Bond Formation: Regioselective C3-Alkylation of Coumarins with Tertiary Amines.Adv. Synth. Catal.,2017,359, 3090; (IF：5.851)

9.Dian L., Zhao H., Zhang-Negrerie D., Du Y.*Cobalt-Catalyzed Twofold Direct C(sp2)−C(sp3) Bond Coupling: Regioselective C-3 Alkylation of Coumarins with (Cyclo)alkyl Ethers.Adv. Synth. Catal.,2016,358, 2422; (IF：5.851)

Abstracted byChemInform,2016,47, 51

Special issue ofBase-metal catalysisedited by Prof.M. Christina Whiteand Prof.Alois Fürstner

8.Dian L., Wang S., Zhang-Negrerie D., Du Y.* Organocatalytic Radical Involved Oxidative Cross-Coupling ofN-Hydroxyphthalimide with Benzylic and Allylic Hydrocarbons.Adv. Synth. Catal.,2015,357, 3836; (IF：5.851)

Abstracted byChemInform,2016,47, 17

7.Dong, T., Li, C., Wang, X.,Dian, L., Zhang, X., Chen, X., Li, L., Cao, R., Huang, N., He, S., Lei, X.* Ainsliadimer A Selectively Inhibits IKKα/β by Covalently Binding a Conserved Cysteine.Nat. Commun.,2015,6, 6522; (IF：12.353)

News story describing this work was highlighted inChem. & Eng. News,2015,15, 39

6.Dian L., Wang S., Zhang-Negrerie D., Du Y.*, Zhao K. Organocatalytic Amination of Alkyl Ethersvia n-Bu4NI/t-BuOOH Mediated Intermolecular Oxidative C(sp3)–N Bond Formation: Novel Synthesis of Hemiaminal Ethers.Chem. Commun.,2014,50, 11738; (IF：6.164)

Abstracted byChemInform,2015, DOI: 10.1002/chin.201509058

One of the 25 most-down loaded in Q3 of2015

5. Zheng Z.,Dian L., Yuan Y., Zhang-Negrerie D., Du Y.*, Zhao K.*PhI(OAc)2-Mediated Intramolecular Oxidative Aryl-Aldehyde Csp2-Csp2Bond Formation: Metal-free Synthesis of Acridone Derivatives.J. Org. Chem.,2014,79,7451;(IF：4.335)

Abstracted byChemInform,2015, DOI: 10.1002/chin.201507225

4.Li C., Dong T.,Dian L., Zhang W., Lei X.* Biomimetic Syntheses and Structural Elucidation of the Apoptosis-inducing Sesquiterpenoid Trimers: (−)-Ainsliatrimers A and B.Chem. Sci.,2013,4, 1163;(IF：9.346)

3. Li, C.,Dian L., Zhang W., Lei X.*Biomimetic Syntheses of (−)-Gochnatiolides A−C and (−)-Ainsliadimer B.J. Am. Chem. Soc.,2012,134, 12414; (IF：14.357)

2.Leng J.-D.,Dian L.-Y., Liu J.-L., Tong M.-L.* Two MnIII4MnII8 Clusters From the Use of Tripodal Ligands Showing Single-Molecule Magnet Behavior.Polyhedron,2011,30, 3088;(IF：2.067)

1.Leng J.-D.,Dian L.-Y., Liu J.-L., Tong M.-L.* A Series of MnIII4MnII8 Single-Molecule Magnets Mediated by Intra- and Intermolecular Interactions.Eur. J. Inorg. Chem.,2011, 2317.(IF：2.507)