Shuangyu Bi

Release date:2019-09-23    Author:     Editor: liyuan    Click:







09.2008 – 07.2013

Peking University

Quantitative Biology


09.2004 – 07. 2008

Ocean University of China

Biological Science

Research Experience




10. 2013 – 08. 2019

Max-Planck-Institute for Terrestrial Microbiology

Postdoctoral fellow

Research Interests

1. Discovery of novel chemoeffectors and signal transduction mechanisms of bacterial networks

2. Design of novel biosensors

3. Dynamics of metabolic networks on single-cell level

Research Projects

01. 2020 – 12. 2024 Taishan Scholar (Young Expert Program)

09. 2019 – 08. 2024 Qilu Young Scholar of Shandong University

Representative Publications

1.Bi, S.1, Jin, F.1, Sourjik, V. Inverted signaling by bacterial chemotaxis receptors.Nat. Commun., 2018, 9:2927.

2. Bi, S., Sourjik, V. Stimulus sensing and signal processing in bacterial chemotaxis.Curr. Opin. Microbiol., 2018, 45:22-29.

3. Bi, S., Pollard, A. M., Yang, Y., Jin, F., Sourjik, V. Engineering hybrid chemotaxis receptors in bacteria.ACS Synth. Biol. 2016, 5:989-1001.

4. Bi, S., & Lai, L. Bacterial chemoreceptors and chemoeffectors.Cell. Mol. Life Sci., 2015, 72:691-708.

5. Reyes-Darias, J., García, V., Rico-Jiménez, M., Corral-Lugo, A., Lesouhaitier, O., Juárez-Hernández, D., Yang, Y.,Bi, S., Feuilloley, M., Muñoz-Rojas, J., Sourjik, V., Krell, Tino. Specific gamma-aminobutyrate (GABA) chemotaxis inPseudomonadswith different lifestyle.Mol. Microbiol., 2015, 97:488-501.

6.Bi, S., Yu, D., Si, G., Luo, C., Li, T., Ouyang, Q., Jakovljevice, V., Sourjik, V., Tu, Y., Lai, L. Discovery of novel chemoeffectors and rational design ofEscherichia coli chemoreceptor specificity.Proc. Natl. Acad. Sci. U.S.A., 2013, 110:16814–16819.

7. Bai, Y., Xue, H., Wang, K., Cai, L., Qiu, J.,Bi, S., Lai, L., Cheng, M., Liu, S., Liu, K. Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket.Amino Acids, 2013, 44:701-713.

8. Si, G., Yang, W.,Bi, S., Luo, C., Ouyang, Q. A parallel diffusion-based microfluidic device for bacterial chemotaxis analysis.Lab Chip, 2012, 12:1389-1394.

Adress:State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao 266237, P.R. China

Tel: (86)-0532-58631501  (86)-0532-58631597  Post Code: 266237

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