Education
Degree |
Date |
Affiliation |
Major |
PhD |
09.2008 – 07.2013 |
Peking University |
Quantitative Biology |
Bachelor |
09.2004 – 07. 2008 |
Ocean University of China |
Biological Science |
Research Experience
Date |
Affiliation |
Position |
10. 2013 – 08. 2019 |
Max-Planck-Institute for Terrestrial Microbiology |
Postdoctoral fellow |
Research Interests
1. Discovery of novel chemoeffectors and signal transduction mechanisms of bacterial networks
2. Design of novel biosensors
3. Dynamics of metabolic networks on single-cell level
Research Projects
01. 2020 – 12. 2024 Taishan Scholar (Young Expert Program)
09. 2019 – 08. 2024 Qilu Young Scholar of Shandong University
Representative Publications
1.Bi, S.1, Jin, F.1, Sourjik, V. Inverted signaling by bacterial chemotaxis receptors.Nat. Commun., 2018, 9:2927.
2. Bi, S., Sourjik, V. Stimulus sensing and signal processing in bacterial chemotaxis.Curr. Opin. Microbiol., 2018, 45:22-29.
3. Bi, S., Pollard, A. M., Yang, Y., Jin, F., Sourjik, V. Engineering hybrid chemotaxis receptors in bacteria.ACS Synth. Biol. 2016, 5:989-1001.
4. Bi, S., & Lai, L. Bacterial chemoreceptors and chemoeffectors.Cell. Mol. Life Sci., 2015, 72:691-708.
5. Reyes-Darias, J., García, V., Rico-Jiménez, M., Corral-Lugo, A., Lesouhaitier, O., Juárez-Hernández, D., Yang, Y.,Bi, S., Feuilloley, M., Muñoz-Rojas, J., Sourjik, V., Krell, Tino. Specific gamma-aminobutyrate (GABA) chemotaxis inPseudomonadswith different lifestyle.Mol. Microbiol., 2015, 97:488-501.
6.Bi, S., Yu, D., Si, G., Luo, C., Li, T., Ouyang, Q., Jakovljevice, V., Sourjik, V., Tu, Y., Lai, L. Discovery of novel chemoeffectors and rational design ofEscherichia coli chemoreceptor specificity.Proc. Natl. Acad. Sci. U.S.A., 2013, 110:16814–16819.
7. Bai, Y., Xue, H., Wang, K., Cai, L., Qiu, J.,Bi, S., Lai, L., Cheng, M., Liu, S., Liu, K. Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket.Amino Acids, 2013, 44:701-713.
8. Si, G., Yang, W.,Bi, S., Luo, C., Ouyang, Q. A parallel diffusion-based microfluidic device for bacterial chemotaxis analysis.Lab Chip, 2012, 12:1389-1394.
