Education

Degree	Date	Affiliation	Major
PhD	1997.9-2001.6	Shandong University	Microbiology
Master	1988.9--1992.6	Shandong University	Microbiology
Bachelor	1982.9--1986.6	Shandong University	Microbiology

Research Experience

Date	Affiliation	Position
2002 .9 – present,	State Key Lab of Microbial Technology, SDU	Professor
1997.9 – 2002.9	State Key Lab of Microbial Technology, SDU	Associate professor
1992.9 – 1997.9	Department of Microbiology, SDU	Lecturer
1986.7 – 1992.9	Department of Microbiology, SDU	Teaching assistant

Research Interests

1.Genetics and physiology of Lactic acid bacteria and their bacteriophages

2. Probiotics and their bioactive metabolites applied in feedstuff additives or bacterial inoculants

3. Lactic acid bacteria used as starter culturesfor dairy fermentation andfermented drink.

Research Projects

1. Construction ofgalactose-positive strains by targeted genmome editing based on the regulation mechanism of galactose metabolism in Streptococcus thermophiles.National Natural Science Foundation of China(No.31871767).2019.1-2018.22

2. Development o ofbacterial inoculants in silage fermention for impoving the silage quality. Public Service Sectors(Agriculture) Special andScientificResearchProjects (No.201503134). 2015.1~2019.12.

3. Characterization of a enzymic defence against the peroxide stress in Streptococcus thermophiles by comparative genome analysis.National Natural Science Foundation of China(No.31471715). 2015.1-2018.12

4. Development of functional probiotics for the intestinal health and nutrient regulation of chicken. National Sci-Tech SupportProgram of China (No.2012BAD39B01) .2012.1-2016.12

5. Functional analysis ofthe lysis mechinsm of the Endolysin and Holin coding by the temperate bacteriophageФYB5 in Lactobacillus fermtrum. National Natural Science Foundation of China （No. 31271905）.2013.1-2016.12

6. Metabolic engineering andmetabolic regulation in Lactic acid bacteria. HI-Tech Research and Development Program of China（No.2011AA100902）. 2011.01—2015.12

7. Construction of a synthetic promoter library and optimization the pyruvate flux from lactic acid to diacelyl.National Natural Science Foundation of China（No.31070091）.2011.01-2013.12

8. Surface Display system in lactic acid bacteria and potential application as delivery vehicles for antigens.National Natural Science Foundation of China (No. 30870023).2008.01-2011.12

Representative Publications

1. Zhenshang Xu, Susu Zhang, Yingli Mu, Jian Kong. Paenibacillus panacisoli enhances growth of Lactobacillus spp. by producing xylooligosaccharides in corn stover ensilages. Carbohydrote Polyers. 2018. 184：435–444.

2. Yongping Xin, Tingting Guo, Yingli Mu and Jian Kong*. Coupling the recombineering to Cre-lox system enables simplified large‑scale genome deletion in Lactobacillus casei. Microb Cell Fact. 2018. 17:21.

3. Zhenshang Xu, Susu Zhang, Rongling Zhang, Shixu Li and Jian Kong. The changes in dominant lactic acid bacteria and their metabolites during corn stover ensiling. Journal of Applied Microbiology. 2018. 125(3):675-685.

4. YueWang,HonghongLi,TiejunLi,JianKong*.Cytoprotective effect of Streptococcus thermophilus against oxidative stress mediated by a novel peroxidase (EfeB).Journal of Dairy Science, 2018, 101(8): 6955-6963.

5. Yongping Xin, Tingting Guo, Yingli Mu and Jian Kong*. A Single-Plasmid Genome Editing System for Metabolic Engineering of Lactobacillus casei. Frontiers in Microbiology. 2018, 9:1-11.

6. Yongping Xin, Tingting Guo, Yingli Mu and Jian Kong*. Development of a counterselectable seamless mutagenesis system in lactic acid bacteria. Microb Cell Fact. 2017. 16:116.

7. Tingting Guo, Li Zhang, Yongping Xin, ZhenShang Xu, Huiying He, Jian Kong . Oxygen-Inducible Conversion of Lactate to Acetate in Heterofermentative Lactobacillus brevis ATCC 367. Applied and Environmental Microbiology. 2017.83(21):1

8. Zhenshang Xu, Huiying He, Susu Zhang & Jian Kong . Effects of inoculants Lactobacillus brevis and Lactobacillus parafarraginis on the fermentation characteristics and microbial communities of corn stover silage.Scientific Reports. 2017. 7: 13614

9. Guo, T., Xin, Y., Zhang, C., Ouyang, X., & Kong, J. The potential of the endolysin Lysdb fromLactobacillus delbrueckiiphage for combatingStaphylococcus aureusduring cheese manufacture from raw milk.Appl Microbiol Biotechnol, 2016. 100:3545–3554.

10. Ting Wang, Zhenshang Xu, Shiyi Lu, Min Xin, Jian Kong*. Effects of glutathione on acid stress resistance and symbiosis between Streptococcus thermophilus and Lactobacillus delbrueckii subsp. Bulgaricus. International Dairy Journal 61, 2016. 22~28

11. Wenwei Lu , Wentao Kong , Pu Yang, Jian Kong*. The Global Regulator CodYst in Streptococcus thermophillus Controls the Metabolic Network for Escalating Growth in the Milk Environment. Applied and Environmental Microbiology. 2015, 81( 7); 2349-2358.

12. Yi Xu, TingWang, Jian Kong*, Hui-Li Wang.Identification and functional characterization of AclB, a novel cell-separating enzyme from Lactobacillus casei. International Journal of Food Microbiology. 2015, 203: 93–100.

13. Chenchen Zhang, Yongping Xin, Yue Wang, Tingting Guo, Shiyi Lu, Jian Kong*. Identification of a Novel Dye-Decolorizing Peroxidase, EfeB, Translocated by a Twin-Arginine Translocation System in Streptococcus thermophilus CGMCC 7.179. Applied and Environmental Microbiology. 2015, 81(18): 6108~6119.

Patents

1. Paenibacillus illinoisensis KWT5 strain which producedbeta、alpha-galactosidase simultaneously.

NL ZL201210580938.6.

2. A method for cocultural lactic acid bacteria and Bacillus sp. NLZL201210581009.7.

3. A liquid starter cultures used foryogurt ZL201410475760.8

一株产生beta、alpha两种半乳糖苷酶的伊利诺类芽孢杆菌及应用	ZL201210580938.6	2014.05.21
一种乳酸杆菌和芽孢杆菌混合培养的方法	ZL201210581009.7	2014.08.13
一种液体酸奶发酵剂的制备方法及其产品与应用	ZL201410475760.8	2017.01.18
一株具有γ-氨基丁酸和谷胱甘肽合成能力的嗜热链球菌及其应用	ZL201410480097.0	2017.02.15
一株产阿魏酸酯酶的噬淀粉乳杆菌及其应用	ZL201510642714.7	2018.02.23
一株产细胞被膜蛋白酶的鼠李糖乳杆菌及其应用	ZL201510642605.5	2018.03.20
一组干酪乳杆菌基因敲除载体及其应用	CN201710696363.7	2017.08.15