Yaohua Zhong

Release date:2019-06-19    Author:     Editor: liyuan    Click:









Shandong University




Northeast Normal University



Research Experience





Shandong University

Associate Professor


Massachusetts Institute of Technology (MIT)

Postdoctoral Associate


Shandong University

Postdoctoral Associate and Lecturer


Research Interests

My research is focused on the protein expression in industry, incuding the protein secretion mechanism in the fungal cells, reconstruction of cellulose-degrading enzyme system for bioethanol production as well as the enzymes engineering for food production. The research approach combines classical cell biology and molecular biology tools with cutting-edge technologies such as RNAseq to engineer the processes that underlie protein production in cells. 

Research Projects

Our research is supported by at least 6 grants from Natioanl the National Natural Science Foundation of China, the National Basic Research Program of China and the Excellent Young and Middle-Aged Scientist Award Grant of Shandong Province of China. 

Representative Publications

Gao J, Qian Y, Wang Y, Qu Y,Zhong Y*. Production of the versatile cellulase for cellulose bioconversion and cellulase inducer synthesis by genetic improvement ofTrichoderma reesei.Biotechnology for Biofuels. 2017,10:272. (*Correspondence)

Qian Y, Zhong L, Gao J, Sun N, Wang Y, Sun G, Qu Y,Zhong Y*. Production of highly efficient cellulase mixtures by genetically exploiting the potentials of Trichoderma reesei endogenous cellulases for hydrolysis of corncob residues.Microbial Cell Factories. 2017,16(1):207. (*Correspondence)

Zhang J, Liu C, Xie Y, Li N, Ning Z, Du N, Huang X,Zhong Y*. Enhancing fructooligosaccharides production by genetic improvement of the industrial fungusAspergillus nigerATCC 20611.Journal of Biotechnology.2017, 249: 25-33. (*Correspondence)

Xie Y, Zhou H, Liu C, Zhang J, Li N, Zhao Z, Sun G,Zhong Y*.A molasses habitat-derived fungusAspergillus tubingensisXG21 with high β-fructofuranosidase activity and its potential use for fructooligosaccharides production.AMB Express.2017,7(1):128. (*Correspondence)

Qian Y, Zhong L, Hou Y, Qu Y,Zhong Y*. Characterization and strain improvement of a hypercellulolytic variant,Trichoderma reeseiSN1, by genetic engineering for optimized cellulase production in biomass conversion improvement.Frontiers in Microbiology ), 2016, 7: 1349. (*Correspondence)

Song W, Han X, Qian Y, Liu G, Yao G,Zhong Y*, Qu Y*. Proteomic analysis of the biomass hydrolytic potentials ofPenicillium oxalicumlignocellulolytic enzyme system.Biotechnology for Biofuels .2016, 9: 68. (*Correspondence)

Zhang X,Zhong Y*, Yang S1, Zhang W, Xu M, Ma A, Zhuang G, Chen G, Liu W*. Diversity and dynamics of the microbial community on decomposing wheat straw during mushroom compost production.BioresouceTechnol(Bioresource Technology). 2014, 170: 183-195. Oct, 2014. (*Correspondence)

Zhong Y, Wang X, Yu H, Liang S, Wang T. Application of T-DNA insertional mutagenesis for improving cellulase production in the filamentous fungus Trichoderma reesei.Bioresource Technology2012, 110: 572–577.

Zhong Y, Yu H, Wang X, Wang T. Towards a novel efficient T-DNA-based mutagenesis and screening system using green fluorescent protein (GFP) as a vital reporter in filamentous fungusTrichoderma reesei.Molecular Biology Reports, 2011, 38 (6): 4145–4151.

Zhong Y, Wang TH, Wang XL, Zhang GT, Yu HN. Identification and characterization of a novel gene, TrCCD1, and its possible function in hyphal growth and conidiospore development ofTrichoderma reesei.Fungal Genetics and Biololgy2009, 46 (3): 255-263. 

Honors and awards

2016 The first prize for the Young College Teachers’ Teaching Ability held by Shandong University


5 patents from National Intellectual Property Administration, P. R. China

Adress:State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao 266237, P.R. China

Tel: (86)-0532-58631501  (86)-0532-58631597  Post Code: 266237

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