Education
Degree |
Date |
Affiliation |
Major |
PhD |
Sep.2009-Jun.,2015 |
University of Science and Technology of China |
Biochemistry and Molecular Biology |
Bachelor |
Sep.2005-Jul.,2009 |
Anhui University |
Biotechnology |
Research Experience
Date |
Affiliation |
Position |
Aug. 2021-Now |
Shandong University |
Associate Research Fellow |
Aug.2017-Jul.2021 |
QIBEBT, Chinese Academy of Sciences |
Postdoctor |
Jun.2015-Jul.2017 |
University of Science and Technology of China |
Post-doc Researcher |
Research Interests
Bacterial Gene Editing Methods, Protein Engineering and Directed Evolution, Microbial Metabolic Engineering , Analysis of Multi-omics by Bioinformatics.
Research Projects
4. Enable engineered strains horizontal optimization by developing new gene editing method and software, National Natural Science Foundation of China(3247088), 2025.01.01- 2028.12.30, PI.
3. A More Universal Bacterial Gene Editing Method, Shandong Provincial Natural Science Foundation(ZR2022QC123), 2023.01.01- 2025.12.30, PI.
2. Key Technologies for Green Manufacturing of Bio-based Rubber - Key Technologies for Bio-based Monomer Preparation(Sub-project 3) , National Key R&D Program (2022YFC2104701-3), 2022.11-2026.10, PI.
1. Efficient Biosynthesis of 3-Hydroxypropionic Acid byKluyveromyces marxianusand Iterative Directed Evolution of Key Enzymes, Guangdong Basic and Applied Basic Research Foundation (2022A1515110047), 2022.10-2025.09, PI.
Representative Publications
9. Zhang, Jia#; Su, Xiaolu#; Wang, Yefei; Wang, Xiaohang; Zhou, Shiqi; Jia, Hui; Jing, Xiaoyan; Gong, Yanhai;Wang, Jichao*; Xu, Jian*.Improved single-cell genome amplification by a high-efficiency phi29 DNA polymerase.Frontiers in Bioengineering and Biotechnology,2023,11:1233856. (among the topmost viewed and downloaded this year's articles)
8. Zhang, Jia; Xu, Teng; Wang, Xiaohang; Jing, Xiaoyan; Zhang, Jia; Hong, Jiong; Xu, Jian;Wang, Jichao*. Lignocellulosic xylitol production from corncob waste by engineeredKluyveromyces marxianus.Frontiers in Bioengineering and Biotechnology,2022, 10:1029203.
7. Zhao, Zhe; Xu, Ying; Jiang, Bo; Qi, Qingsheng; Tang, Ya-Jie; Xian, Mo;Wang, Jichao*; Zhao, Guang*. Systematic Identification of CpxRA-Regulated Genes and Their Roles in Escherichia coli Stress Response.mSystems, 2022, e00419-22.
6. Hu, Shenglin; Wang, Zhefan; Wang, Dongmei;Wang, Jichao*; Hong, Jiong*. The development of a heterologous gene expression system in thermophilic fungusThermoascus aurantiacus.3 Biotech, 2021, 11(9): 1-15.
5. Li, Shihua#; Yu, Kai#; Wu, Guandi#; Zhang, Qingfeng; Wang, Panqin; Zheng, Jian; Liu, Ze-Xian;Wang, Jichao*; Gao, Xinjiao*; Cheng, Han*. pCysMod: Prediction of Multiple Cysteine Modifications Based on Deep Learning Framework.Frontiers in Cell and Developmental Biology, 2021, 9:617366..
4.Wang, Jichao#; Sui, Xinyue#; Ding, Yamei; Fu, Yingxin; Feng, Xinjun; Liu, Min; Zhang, Youming; Xian, Mo*; Zhao, Guang*. A fast and robust iterative genome-editing method based on a Rock-Paper-Scissors strategy.Nucleic Acids Research, 2021, 49(2): e12-e12.
3. Liu, Xiutao; Feng, Xinjun; Ding, Yamei; Gao, Wenjie; Xian, Mo;Wang, Jichao*; Zhao, Guang*. Characterization and directed evolution of propionyl-CoA carboxylase and its application in succinate biosynthetic pathway with two CO2fixation reactions.Metabolic Engineering, 2020, 62: 42-50.
2. Yu, Xiao; Afreen, Shagufta; Kong, Qingshan*;Wang, Jichao*. Study on Self-Assembled Morphology and Structure Regulation of alpha-Zein in Ethanol-Water Mixtures.Langmuir, 2020, 36(40): 11975-11984.
1.Wang, Jichao; Zhang, Tongchuan; Liu, Ruicun; Song, Meilin; Wang, Juncheng; Hong, Jiong; Chen, Quan*; Liu, Haiyan*. Recurring sequence-structure motifs in (βα)8-barrel proteins and experimental optimization of a chimeric protein designed based on such motifs. Biochimica et Biophysica Acta-Proteins and Proteomics, 2017, 1865(2): 165-175.
