Education
Degree |
Date |
Affiliation |
Major |
PhD |
2018.06 |
Shandong University |
Medicinal Chemistry |
Bachelor |
2012.06 |
Shandong University |
Pharmaceutical Sciences |
Research Experience
Date |
Affiliation |
Position |
2022.2-Now |
Shandong University State Key Laboratory of Microbial Technology |
Assistant Professor |
2018.7-2022.2 |
Shandong University State Key Laboratory of Microbial Technology |
Postdoctoral Fellow |
2017.4-2018.5 |
Texas A&M University Health Science Center, Institute of Biosciences and Technology |
Visiting Scholar |
Research Interests
1. Tumor Targeting Bacteria Based Anti-Tumor Therapy
2. Optical Biosensors for Analysis of Biological Importance
Research Projects
1. 2023.01-2027.12, Future Plan for Young Scholars of Shandong University.
2. 2023.01-2025.12, Tumor targeting bacteria based imageable vehicle heterogeneous express and deliver Romidepsin for cancer therapy. Youth Program of National Natural Science Foundation of China (No. 32201245).
3. 2021.1-2023.12, BRET based bacterial imageable system. Shandong Provincial Natural Science Foundation (ZR2020QB158).
4. 2020.10-2023.9, Coelenterazine bioluminescence based bacterial imageable system. Guangdong Basic and Applied Basic Research Foundation (2020A1515110284).
Representative Publications
1. Chenghao Ma; Jingxi Liu; Hongjing Liu; Xiaohan Zhao; Geng Li; Youming Zhang*; Tianyu Jiang*; Tumor-targeting bioluminescent bacteria for in vivo imaging, Engineering Microbiology, 2025, accepted.
1.Tianyu Jiang；Xiaoyu Bai; Minyong Li*；Advances in the Development of Bacterial Bioluminescence Imaging, Annual Review of Analytical Chemistry, 2024, 17(1): 265-288.
2. Tianyu Jiang*; Jingwen Song; Youming Zhang*; Coelenterazine-Type Bioluminescence-Induced Optical Probes for Sensing and Controlling Biological Processes, International Journal of Molecular Sciences, 2023, 24, 5074.
3. Qi Gao; Sizhe Deng; Tianyu Jiang*; Recent developments in the identification and biosynthesis of antitumor drugs derived from microorganisms, Engineering Microbiology, 2022, 2(4).
4. Yuexin Wu; Tianyu Jiang*; Developments in FRET- and BRET-Based Biosensors, Micromachines, 2022 Oct 20;13(10):1789.
5. Tianyu Jiang ; Minyong Li*; Synthetic Coelenterazine Derivatives and Their Application for Bioluminescence Imaging, Methods in molecular biology, 2022 July; 2524:17-36.
6. Ancheng Ouyang; Dongmu Zhao; Xianglei Wang; Wei Zhang; Tianyu Jiang*; Aiying Li*; Wei Liu*; Covalent RGD-graphene-phthalocyanine nanocomposite for fluorescence imaging-guided dual active/passive tumor-targeted combinatorial phototherapy, Journal of Materials Chemistry B, 2022, 10(2): 3 06-320
7. Tianyu Jiang*#; Xingye Yang#; Geng Li; Xiaohan Zhao; Tao Sun; Rolf Müller; Hailong Wang*; Minyong Li*; Youming Zhang*; Bacteria-Based Live Vehicle for In Vivo Bioluminescence Imaging, Analytical Chemistry, 2021, 93(47): 15687-15695
8. Elena V. Eremeeva#; Tianyu Jiang#; Natalia P. Malikova; Minyong Li*; Eugene S. Vysotski*; Bioluminescent Properties of Semi-Synthetic Obelin and Aequorin Activated by Coelenterazine Analogues with Modifications of C-2, C-6, and C-8 Substituents, International Journal of Molecular Sciences, 2020, 21(15): 5446-5446
9. Tianyu Jiang; Peng Zhu; Lupei Du; Minyong Li*; Identification of AI-2 Quorum Sensing Inhibitors in Vibrio harveyi Through Structure-Based Virtual Screening, Methods in molecular biology (Clifton, N.J.) 2018;1673:353-362.
10. Tianyu Jiang; Xingye Yang; Yubin Zhou; Ilia Yampolsky; Lupei Du; Minyong Li*; New bioluminescent coelenterazine derivatives with various C-6 substitutions, Organic & Biomolecular Chemistry, 2017, 15(33): 7008-7018
11. Tianyu Jiang#; Bowen Ke#; Hui Chen; Weishan Wang; Lupei Du; Keqian Yang; Minyong Li*; Bioluminescent Probe for Detecting Mercury(II) in Living Mice, Analytical Chemistry, 2016 Aug 2;88(15):7462-5.
12. Tianyu Jiang; Xiaofeng Yang; Xingye Yang; Mingliang Yuan; Tianchao Zhang; Huateng Zhang; Minyong Li*; Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution for Renilla luciferase, Organic & Biomolecular Chemistry, 2016 Jun 21;14(23):5272-81.
13. Tianyu Jiang; Weishan Wang; Xingkang Wu; Wenxiao Wu; Haixiu Bai; Zhao Ma; Yuemao Shen; Keqian Yang*; Minyong Li*; Discovery of New Substrates for LuxAB Bacterial Bioluminescence, Chemical Biology and Drug Design, 2016 Aug;88(2):197-208.
14. Tianyu Jiang; Lupei Du; Minyong Li*; Lighting up bioluminescence with coelenterazine: strategies and applications, Photochemical & Photobiological Sciences, 2016 Apr;15(4):466-80.
15. Tianyu Jiang; Minyong Li*; Quorum sensing inhibitors: a patent review, Expert Opinion on Therapeutic Patents, 2013 Jul;23(7):867-94.
Honors and awards
Third Prize in Teaching Competition of State Key Laboratory of Microbial Technology
Patents
Chinese patents：202411904503，2021105472047
