Education
Degree |
Date |
Affiliation |
Major |
PhD |
2005.09–2010.07 |
Shandong University |
Microbiology |
Master |
|
|
|
Bachelor |
1999.09–2003.07 |
Shandong Normal University |
Biology |
Research Experience
Date |
Affiliation |
Position |
2015.06– |
Microbial Technology Insitute,Shandong University |
Associate Professor |
2014.1–2015.6 |
Bioengineering Department, University of Illinois at Urbana-Champaign, US |
Postdoctor |
2011.4–2013.12 |
E2FTC center,Myongji University, South Korea |
Postdoctor |
Research Interests
Environmental Microbiology, Microbial physiology and biochemistry, Metabolic Engineering, Microbial sulfur metabolism
Research Projects
National Natural Science Foundation of China (31770093, 2018.01–2021.12, 550,000 ¥);
Natural Science Foundation of Shandong Province (ZR2016CM03, 2016.11-2019.06,550,000 ¥);
Natural Science Foundation of Shandong Province (ZR2017ZB0210Z, 2017.09-2019.08,180,000 ¥);
Representative Publications
1. Hu X, Li H, Zhang X, Chen Z, Zhao R, Hou N, Liu J, Xun L, Liu H*. Developing polysulfide-sensitive GFPs for real-time analysis of polysulfides in live cells and subcellular organelles.Anal Chem. 2019. doi: 10.1021/acs.analchem.8b04634.
2. Valdehuesa KNG, Ramos KRM, Nisola GM, Bañares AB, Cabulong RB, Lee WK*, Liu H*, Chung WJ*. Everyone loves an underdog: metabolic engineering of the xylose oxidative pathway in recombinant microorganisms.Appl Microbiol Biotechnol.2018. doi: 10.1007/s00253-018-9186-z
3. Li H, Li J, Lü C, Xia Y, Xin Y, Liu H, Xun L*, Liu H*. FisR activates σ54 -dependent transcription of sulfide-oxidizing genes inCupriavidus pinatubonensisJMP134.Mol Microbiol.2017. 105(3):373-384.
4. Xin Y, Liu H, Cui F, Liu H, Xun L. RecombinantEscherichia coliwith sulfide:quinone oxidoreductase and persulfide dioxygenase rapidly oxidises sulfide to sulfite and thiosulfate via a new pathway.Environ Microbiol. 2016. 18(12):5123-5136
5. Liu H, Lu T*. Autonomous production of 1,4-butanediol via a de novo biosynthesis pathway in engineeredEscherichia coli.Metab Eng. 2015. 29:135-141.
6. Liao C, Seo SO, Celik V, Liu H, Kong W, Wang Y, Blaschek H, Jin YS, Lu T. Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation byClostridium acetobutylicum.Proc Natl Acad Sci U S A. 2015. 112(27):8505-10.
7. Liu H, Wang Y, Tang Q, Kong W, Chung WJ, Lu T*. MEP pathway-mediated isopentenol production in metabolically engineeredEscherichia coli. Microb Cell Fact. 2014. 13:135.
Patents
1. Wook-Jin Chung, Huaiwei Liu, Kris Nino Gomez Valdehuesa, Kristine Rose Medina Ramos, Mi-Deok Han. Recombinant Escherichia coli producing D-xylonic acid from D-xylose and method for producing D-xylonic acid using the same. US patent 20130084612 A1.
2. Wook-Jin Chung, Huaiwei Liu. Microorganisms producing ethane-1, 2-diol, and method using same for producing ethane-1, 2-diol，2013.02.05，WIPO，PCT/KR2013/000917.
