Education

Research Experience

Research Interests

1. Diversity, systematics of marine microbes and the culture technology from them

2. Ecological functions and environmental adaptation mechanisms of marine microbes

3. Enzymes from marine microbes

Research Projects

1. The coexistence and interaction mechanism of the copiotrophic and oligotrophic bacteria in the oceanic surface seawater: a case study of Pseudoalteromonas sp. W04 and Brachybacterium sp. Y09 (2021-2024,National natural science foundation of China, 42076151)

2.Studies on the role and mechanism of deep-sea bacteria and their extracellular M23 family proteases in the recycling of deep-sea peptidoglycan (2017-2020, National natural science foundation of China, 31670063)

3. Studies on the degradation mechanism on collagens of a novel collagenolytic protease from a deep-sea bacterium and the functions of its C-terminal domain. (2012-2015, National natural science foundation of China, 31170055)

4. Development and application potential evaluation of new biological products of polar microorganisms (2018-2021, National key research and development program, 2018YFC1406704)

5.Microbial diversity of seamounts (2017-2021, Science and technology basic resources investigation program of China, 2017FY100804)

Representative Publications

1．Xiao-Yan He, Ning-Hua Liu, Ji-Qing Liu, Ming Peng, Zhao-Jie Teng, Tie-Ji Gu, Xiu-Lan Chen, Yin Chen, Peng Wang, Chun-Yang Li, Jonathan D Todd, Yu-Zhong Zhang*, Xi-Ying Zhang*(2023) SAR92 clade bacteria are potentially important DMSP degraders and sources of climate-active gases in marine environments. mBio, 14(6): e0146723.

2. Ning-Hua Liu, Jun Ma, Si-Qi Lin, Kui-Dong Xu, Yu-Zhong Zhang, Qi-Long Qin*, Xi-Ying Zhang* (2023) Biogeographic distribution patterns of the bacterial and archaeal communities in two seamounts in the Pacific Ocean. Frontiers in Marine Science. 10: 1160321.

3．Yan Wang, Hai-Nan Su, Hai-Yan Cao, Si-Min Liu, Shi-Cheng Liu, Xia Zhang, Peng Wang, Chun-Yang Li, Yu-Zhong Zhang, Xi-Ying Zhang*, Xiu-Lan Chen* (2022) Mechanistic insight into the fragmentation of type I collagen fibers into peptides and amino acids by a Vibrio collagenase. Applied and Environmental Microbiology, 88(7): e0167721.

4. Jian Li, Jun-Hui Cheng, Zhao-Jie Teng, Zhong-Zhi Sun, Xiao-Yan He, Peng Wang, Mei Shi, Xiao-Yan Song, Xiu-Lan Chen, Yu-Zhong Zhang, Xinmin Tian*, Xi-Ying Zhang* (2021) Taxonomic and enzymatic characterization of Flocculibacter collagenilyticus gen. nov., sp. nov., a novel gammaproteobacterium with high collagenase production. Frontiers in Microbiology, 12: 621161.

5. Shan Zhang, Wei-Xiong Liu, Ning-Hua Liu, Xiao-Yan He, Hai-Nan Su, Chun-Yang Li, Yu-Zhong Zhang, Xiao-Yan Song, Xi-Ying Zhang* (2020).Antarcticimicrobium sediminisgen. nov., sp. nov., isolated from Antarctic intertidal sediment, transfer ofRuegeria luteatoAntarcticimicrobiumgen. nov. asAntarcticimicrobium luteumcomb. nov. InternationalJournal of Systematic and Evolutionary Microbiology 70(4): 2624-2631.

6. Xiu-Lan Chen#, Jin-Yu Yang#, Xiao-Yu Zheng, Qi Sheng, Lei Wang, Yu-Zhong Zhang, Qi-Long Qin*, Xi-Ying Zhang* (2019) Tripeptides from casein are signal molecules to induce the expression of the extracellular protease MCP-01 gene in marine bacterium Pseudoalteromonas sp. SM9913. Frontiers in Microbiology, 10: 1354.

7. Ping-Yi Li, Qiong-Qiong Yao, Peng Wang, Yi Zhang, Yue Li, Yan-Qi Zhang, Jie Hao, Bai-Cheng Zhou, Xiu-Lan Chen *, Mei Shi, Yu-Zhong Zhang and Xing-Ying Zhang*, A novel subfamily esterase with a homoserine transacetylase-like fold but no transferase activity. Applied and Environmental Microbiology, 2017, 83(9): pii: e00131-17.

8. Ning Wang#, Fei Xu#, Xi-Ying Zhang*, Xiu-Lan Chen, Qi-Long Qin, Bai-Cheng Zhou, Yu-Zhong Zhang, Mei Shi* (2017)Changchengzhania luteagen. nov., sp. nov., a new member of the familyFlavobacteriaceaeisolated from Antarctic intertidal sediment. Journal of Systematic and Evolutionary Microbiology, 67(12):5187-5192.

9. Xi-Ying Zhang, Xiao-Xu Han, Xiu-Lan Chen, Hong-Yue Dang, Bin-Bin Xie, Qi-Long Qin, Mei Shi*, Bai-Cheng Zhou, Yu-Zhong Zhang (2015) Diversity of cultivable protease-producing bacteria in sediments of Jiaozhou Bay, China. Frontiers in Microbiology, 6: 1021.

10. Ping-Yi Li, Xiu-Lan Chen, Peng Ji, Chun-Yang Li, Peng Wang, Yi Zhang, Bin-Bin Xie, Qi-Long Qin, Hai-Nan Su, Bai-Cheng Zhou, Yu-Zhong Zhang, Xi-Ying Zhang* (2015) Interdomain hydrophobic interactions modulate the thermostability of microbial esterases from the hormone-sensitive lipase family. Journal of Biological Chemistry, 290(17): 11188-11198.

11. Chun-Yang Li, Xiu-Lan Chen, Qi-Long Qin, Peng Wang, Wei-Xin Zhang, Bin-Bin Xie, Hai-Nan Su, Xi-Ying Zhang*, Bai-Cheng Zhou, Yu-Zhong Zhang (2015) Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacterium Pseudoalteromonas sp. strain SM9913. Journal of Bacteriology, 197(6): 1125-1134.

12. Li-Yuan Ran, Hai-Nan Su, Ming-Yang Zhou, Lei Wang, Xiu-Lan Chen, Bin-Bin Xie, Xiao-Yan Song, Mei Shi, Qi-Long Qin, Xiuhua Pang, Bai-Cheng Zhou, Yu-Zhong Zhang*, Xi-Ying Zhang* (2014) Characterization of a novel subtilisin-like protease myroicolsin from deep sea bacterium Myroides profundi D25 and molecular insight into its collagenolytic mechanism. Journal of Biological Chemistry, 289(9): 6041-6053.

13. Qi-Long Qin#, Xi-Ying Zhang#, Xu-Min Wang, Gui-Ming Liu, Xiu-Lan Chen, Bin-Bin Xie, Hong-Yue Dang, Bai-Cheng Zhou, Jun Yu, Yu-Zhong Zhang* (2010) The complete genome ofZunongwangia profundaSM-A87 reveals its adaptation to the deep-sea environment and ecological role in sedimentary organic nitrogen degradation. BMC Genomics, 11:247.